الفهرس 
Postoperative Pain and Antimicrobial Efficacy of Augmentin and Metronidazole Antibiotic Paste versus Calcium Hydroxide Paste as an Intra Canal Medication in Cases with Periapical Periodontitis: A Randomized Clinical Trial
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Abstract
This study was conducted as a double blind randomized clinical trial for the assessment and comparison of postoperative pain and antibacterial effect following intracanal medications with augmentin and metronadiazole mixture and calcium hydroxide paste in patients having single rooted teeth diagnosed with necrotic pulp and symptomatic apical periodontitis. Forty participants aged between 18-60 years were included in the study. Only necrotic single rooted teeth with symptomatic apical periodontitis were selected and treated in two visits. For the first visit, following access cavity preparation and root canal instrumentation using ProTaper Universal rotary NiTi instruments, the participants were randomly assigned into two equal groups according to the intracanal medication applied: Metronidazole (500 mg) and Augmentin (1 gram) mixture paste. Calcium hydroxide paste (Ultracal XSTM, Ultradent Products, Inc, South Jordan, Utah, USA.) The intracanal medications were applied into the canals with Lentulo spiral and left inside the canals for 1 week. The participants were given a pain diary for postoperative pain recoding, They ranked their postoperative pain level at 6, 12, 24, 48, 72 hours, and 7th day on a numerical rating scale (NRS) in the pain diary. Obturation was performed in the second visit using lateral condensation technique. Summary and Conclusion 102 Results revealed that there was no statistically significant difference between the two groups in postoperative pain intensity or in their antibacterial effect. Within the limitations of this study, the following could be concluded that: Both groups were effective and that all cases cultured bacteria at initial samples (S1) confirming the strong correlation between bacteria and apical periodontitis