الفهرس 
Systematic review and meta-analysis of snoring and apnea hypopnea indices in patients with obstructive sleep apnea treated by mandibular advancement device and continuous positive airway pressure
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Abstract
Implication for practice Based on the results of this review, it seems that the prolonged use of MAD (more than one year) is as effective as CPAP in reducing the AHI. Quality of evidence, however, is very low, which might weaken the recommendations. Implications for research We need further properly conducted and designed RCTs with follow up periods longer than one year, reporting snoring index, apnea hypopnea index, excessive daytime sleepiness and health quality of life score outcomes. These trials should have calculated sample sizes and a wash out period of at least two weeks between the treatments. The methodology should have adequate random sequence generation, allocation concealment, with proper management of incomplete data and reported as recommended by the CONSORT statement (www.consort.org)