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Abstract Objective:The aim of study is to detect the effect of insertion of 400 micrograms rectal misoprostol given preoperatively with catheterization and 400 micrograms rectal misoprostol after closure of abdomen to reduce amount of intraoperative and early postoperative blood loss during elective repeated lower segment caesarean section. Study design:Double blinded randomized interventional prospective controlled study showing impact of preoperative rectal 400 microgram misoprostol and 400 micrograms rectal misoprostol after closure of abdomen on operative and postoperative blood loss in women section undergoing elective lower segment caesarean section. The Study included 200 women undergoing elective cesarean delivery under spinal anesthesia, patients included in the study will be randomized into 2 groups:group (A) (Study group): 100 women who will receive 400 micrograms rectal misoprostol preoperatively with catheterization prior to skin incision and 400 micrograms rectal misoprostol after closure of abdomen and receiving the standard treatment in form of 20 IU oxytocin drip on 500 ml lactated Ringer’s solution over half an hour immediately after delivery of the neonate.group (B) (Control group): 100 women who will receive only the standard treatment in form of 20 IU oxytocin drip on 500 ml lactated Ringer’s solution over half an hour immediately after delivery of the neonate |