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العنوان
Formulation and evaluation of antifungal drug in certain dermatological dosage forms /
الناشر
Nehal Naeem Eltabey Elfar ,
المؤلف
Nehal Naeem Eltabey Elfar
هيئة الاعداد
باحث / Nehal Naeem Eltabey Elfar
مشرف / Mohamed Ahmed Elnabarawi
مشرف / Mahmoud Hassan Teaima
مشرف / Mohamed Ahmed Elnabarawi
تاريخ النشر
2018
عدد الصفحات
148 P. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
العلوم الصيدلية
تاريخ الإجازة
7/11/2018
مكان الإجازة
جامعة القاهرة - كلية الصيدلة - Pharmaceutics
الفهرس
Only 14 pages are availabe for public view

from 183

from 183

Abstract

Fluconazole (FLZ) is a broad spectrum antifungal agent. It has a broad spectrum activity and inhibits nearly all clinically relevant dermatophytes, yeasts, and moulds. Thus, Fluconazole has proven useful for a wide variety of superficial dermatoses. Fluconazole inhibit cytochrome P450 that converts lanosterol to ergosterol, and is required in fungal cell membrane synthesis The aim of the work in this thesis was to formulate Fluconazole in certain topical dosage forms suitable for the patient to treat different skin fungal diseases. The work in this thesis is divided into four chapters namely: >Chapter I: Formulation and Evaluation of Fluconazole in Different Hydrogels Dosage Forms. >Chapter II: Formulation and Evaluation of Fluconazole in Different Emulgels Dosage Forms. >Chapter III: Formulation and Evaluation of Fluconazole in Different Microemulsion based hydrogels Dosage Forms. >Chapter IV: Antifungal activity of Different selected prepared Fluconazole Dosage Forms