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العنوان
The possible antinociceptive effect of Fistin in a rat model of neuropathic pain /
المؤلف
El Sebaei, Asmaa Att Allah Mohammed.
هيئة الاعداد
باحث / Asmaa Attallah Mohammed Elsebaei
مشرف / Prof. Dr. Jehan Moustafa Sorour
مشرف / Dr. Sherine Abdel Salam
مناقش / Prof. Dr. Abeer Abd Elmenem Elwakil
الموضوع
Antinociceptive. Pain.
تاريخ النشر
2023.
عدد الصفحات
124 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
البيطري
تاريخ الإجازة
17/1/2023
مكان الإجازة
جامعة الاسكندريه - كلية العلوم - Zoology
الفهرس
Only 14 pages are availabe for public view

from 113

from 113

Abstract

Neuropathic pain (NP) is known as the chronic pain originating from abnormal functioning or injury to the central or peripheral nerve system (Woolf, 2004; Attal et al., 2006). The International Association for the Study of Pain (IASP) currently defines NP as pain brought on by a somatosensory nervous system injury or disease (Jensen et al., 2011). Despite the fact that pain is a basic alarm system and necessary for survival, NP are serious disorders of the neurological system (Le Bars et al., 2001; Scholz & Woolf, 2002).The modern analgesics that reduce NP are opioids, non-steroidal anti-inflammatory medications, and tricyclic antidepressants. Although they have the ability to inhibit neural activity, they are not sufficiently effective at reducing the progression of disease. Additionally, these medications have serious toxicities and dose-restricting side effects such dependence, addiction, lightheadedness, diarrhea, and fainting (Ji et al., 2014). Despite their harmful side effects, opioids continue to rule the therapeutic landscape (Dai et al., 2020). Therefore, the need to use other natural medications with no side effects emerged, leading in the use of the dietary botanicals.