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Abstract Despite the huge advances done in understanding the pathphysiology of ACS during the past century and the important achievements in finding out the risk factors, diagnosis and management of this condition, it is still considered the most common cause of death worldwide. Diagnosis of ACS is a life-saving process. Among the investigations done in ACS diagnosis, the use of cardiac-specific Troponin I is the preferred, sensitive, specific, and highly accurate biomarker of myocardial necrosis, but their levels do not become detectable until at least 3-6 hours after the onset of symptoms.This necessitate searching for a more rapid promising predictor to improve the diagnostic work up in the first hours. Platelets play a crucial role in the subsequent thrombus formation, leading to myocardial infarction. An increased MPV as an indicator of larger, more reactive platelets may represent a risk factor for myocardial infarction. This study was carried out to assess the association between MPV measurement and cardiac Troponin I in patients admitted with a suspected diagnosis of ACS and to study the value of the MPV as a potential predictive risk factor in the diagnostic workup for ACS. |