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العنوان
Study of the relation between follicle stimulating hormone receptor gene polymorphism and ovarian stimulation response /
الناشر
Sondos Mohammed Mohammed Salem ,
المؤلف
Sondos Mohammed Mohammed Salem
هيئة الاعداد
باحث / Sondos Mohammed Mohammed Salem
مشرف / Mohamed Amr Hussein Elnoury ,
مشرف / Sherif Mohammed Khattab ,
مشرف / Osama Mahmoud Azmy ,
مشرف / WAEL THARWAT EL GARF
تاريخ النشر
2016
عدد الصفحات
272 P. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
تكنولوجيا الموجات فوق الصوتية والأشعة
تاريخ الإجازة
9/3/2016
مكان الإجازة
جامعة القاهرة - المعهد القومى لعلوم الليزر - Medical Applications of Laser
الفهرس
Only 14 pages are availabe for public view

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Abstract

Objective: The aim of the study was to assess the potential of follicle-stimulating hormone receptor (FSHR) gene polymorphism for predicting ovarian response to FSH stimulation. Results: Among Egyptian women, the frequency of the Asn/Asn genotype was significantly more prevalent in the poor responder group (65.3%) compared with the good responder group (24.0%) (P< 0.05); the Ser/Asn genotype was seen in 34.7% of poor responders compared with 64% of good responders and the Ser/Ser phenotype was seen only in good responders (12%). Conclusion: It was found that polymorphism +2039A>G (p.Asn680Ser) of FSHR could be suggested as a good predictor of ovarian response upon controlled FSH stimulation. Medical Research Journal 2014, 13:61{u2013}67