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العنوان
The possible protective role of mango (mangifera indica L.) polysaccharides against cyclophosphamide toxicity in male albino rats /
الناشر
Sara Mohamed Hassan Elaskalany ,
المؤلف
Sara Mohamed Hassan Elaskalany
هيئة الاعداد
باحث / Sara Mohamed Hassan Elaskalany
مشرف / Fathi Mohamed Abdelgleel
مشرف / Ahmed Ibrahim Amein
مشرف / Sohair Ramadan Fahmy
تاريخ النشر
2016
عدد الصفحات
129 P. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
Biochemistry
تاريخ الإجازة
28/2/2017
مكان الإجازة
جامعة القاهرة - كلية العلوم - Biochemistry
الفهرس
Only 14 pages are availabe for public view

from 156

from 156

Abstract

The present study aims to evaluate the possible protective role of polysaccharides extracted from the Egyptian mango mangifera indica L. (MPS) against cyclophosphamide (CP) hepatotoxicity and nephrotoxicity in male albino rats. The MPS revealed significant protective effect against liver and kidney injuries as demonstrated by enhancement of their function parameters as well as histopathological findings. The observed data also showed the antioxidant effect of MPS by decreasing the level of malondialdehyde (MDA) and increasing the level of reduced glutathione (GSH) as well as normalized the activities of the antioxidant enzyme glutathione-S-transferase (GST) and superoxide dismutase (SOD). In conclusion, the recorded results of the present study support the protective role of MPS and silymarin against CP- induced hepatic and renal damage