الفهرس 
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Abstract
Sepsis is the systemic response to infection by microbial organisms and is considered the leading cause of mortality in patients admitted to intensive care units (ICUs). The signs and symptoms of sepsis are highly variable and are influenced by many factors, including the virulence and bio burden of the pathogen, the portal of entry, and the host susceptibility. Early diagnosis of sepsis is often difficult in clinical practice, whilst it can be vital for positive patient outcomes in sepsis management. Any delay in diagnosis and treatment may lead to significant organ failure and can be associated with elevated mortality rates.