الفهرس 
Using optical coherence tomography angiography to correlate peripapillary capillary density to papilledema grade in idiopathic intracranial hypertension
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Abstract
Purpose: Evaluation of the peripapillary microvascular density and neuronal changes in patients with idiopathic intracranial hypertension (IIH) in correlation with the clinical degree of papilledema at time of presentation.
Methods: This case-control study was carried out on 112 eyes of 84 individuals. They were divided into IIH with papilledema group 56 eyes of 28 patients and healthy control group 56 eyes of 56 age and sex matched healthy controls. Optical coherence tomography angiography (OCTA) to assess the peripapillary capillary vessel density (CVD) was done in addition to coloured fundus photography for documentation of papilledema.
Primary outcomes: to measure of vessel density (VD) of the radial peripapillary capillary plexus in IIH cases with papilledema.
Secondary outcomes: to correlate between the peripapillary radial capillary plexus vessel density, RNFLT with the clinical degree of papilledema.
Results: The difference in vessel density and RNFL were statistically significant between both groups with lower vessel density and thicker RNFL in the IIH group. The nerve fiber layer thickness was correlated with the degree of papilledema.
Conclusion: OCT-A revealed a decrease in peripapillary vessel density, which could be related to the swelling of axons in the peripapillary retina caused by papilledema, which increased the thickness of the RNFL.
Overall, OCT-A has the ability to quantify vessel density, identify areas of non-perfusion, and detect early ischemic abnormalities in patients with IIH before they develop optic atrophy and gliosis