الفهرس | Only 14 pages are availabe for public view |
Abstract The metabolic syndrome is becoming one of the major health issues in developing countries . Metabolic syndrome is a group of risk factors that predispose to cardiovascular diseases (CVD) . They include: central obesity, raised triglycerides (TG), low high-density lipoprotein cholesterol (HDL-C), raised blood pressure (BP) and raised fasting blood glucose. Presence of three or more of these risk factors indicates metabolic syndrome. It is also associated with a pro-thrombotic and a pro-inflammatory state .Thyroid hormones affect lipid metabolism, carbohydrate metabolism, blood pressure and energy homeostasis. Studies have given evidence of these effects of thyroid hormones in thyroid disease and recent data have suggested that there may be some association between serum thyroid function in the normal range and components of metabolic syndrome.Thyroid-stimulating hormone (TSH) correlates directly with insulin resistance, TG and indirectly with HDL-C in subjects with normal thyroid function. Decreasing thyroid function in the normal range is associated with occurrence of obesity and hence can potentially contribute to the development of metabolic syndrome.The aim of our study was to determine prevalence of thyroid disorders in patients with metabolic syndrome attending Zagazig University Outpatient Clinics. It included 82 women who met the inclusion criteria of metabolic syndrome according to IDF 2006 as follow : Central obesity as defined by ethnic/racial, specific WC(>102cm for male and >88cm in female)(BMI>30 kg/m2) , and two of the following Triglycerides 150 mg/dl , HDL-C: <40 mg/dl for men, <50 mg/dl for women ,BP 130/85 mm Hg and FPG 100 mg/dl. |