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Abstract Introduction: Focal atrial tachycardia of nonsinus origin, commonly referred to as ectopic atrial tachycardia (EAT), is an uncommon but difficult disorder in children that can lead to a tachycardia-induced cardiomyopathy if sufficiently rapid and incessant. Arrhythmia induced cardiomyopathy management should focus on concerted attempts to eliminate or control the arrhythmia, with the goal of improving symptoms, reversing LV dysfunction, and preventing arrhythmia recurrence. Aim: The aim of this study was to assess the clinical profile of ectopic atrial tachycardia in children and it`s effect on cardiac function. Methods: This study evaluated thirty pediatric patients of Ectopic Atrial tachycardia with structural normal heart from A Tertiary Referral Center at Cairo University Children Hospital. Data obtained included clinical presentation, ECG, Holter, echocardiographic evaluation, response to antiarrhythmic therapy. Results: This showed that 13 out of 30 patients (43.3%) had resolution of EAT and stopped anti-arrhythmic therapy at last follow-up, while 8 out of 30 patients (27%) continued on anti-arrhythmic therapy with suppression of EAT, moreover 8 out of 30 patients (27%) were persistent EAT despite ongoing medical treatment and 1of 30 patients (3%) died at our PICU dt uncontrolled atrial tachycardia. Conclusions: Ectopic atrial tachycardia can be managed successfully in children despite no standardized approach. A miodarone is a good antiarrhythmic agent for the short- and tong-term management of ectopic atrial tachycardia. Children with EAT often present with incessant tachycardia and tachycardia-induced cardiomyopathy. The huge useful effect of heart rate control on cardiac function is clearly demonstrated in our patient. |