الفهرس 
Central venous catheter related neonatal sepsis
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Abstract
Vascular catheters are considered ‘‘life lines,’’ indispensable in neonatal intensive care (NICU).Catheter-related bloodstream infection (CRBSI) is defined as the presence of bacteremia originating from an intravenous catheter. It is one of the most frequent, lethal, and costly complications of central venous catheterization and also the most common cause of nosocomial bacteremia.
Aim of study: To carry out a systematic review of the risk factors for CVC-associated infection in the neonatal populationby comparing central venous catheter CVC and umbilical catheter UC
Methods: The study was conducted on 80 neonates who were admitted to the NICUs of pediatric hospitals, Cairo University, and the Ministry of health pediatric hospitals in Alexandria City. Forty cases were recruited from each. Half of the cases had central venous catheters (70% were non tunneled femoral catheter and 30% were non tunneled internal jugular) and the other half had umbilical catheters. We included neonates with a gestational age of 34 weeks who were sepsis free before the insertion of the central catheter. Complete natal, prenatal, and postnatal histories were taken, and laboratory and radiological investigations were done for all cases. Hematologic scoring system (HSS) was used to assess sepsis occurrence.
Results: There was no statistically significant difference between CVC group and UC group as regards sepsis score with mean Sepsis score was 2.53 for CVC and 2.63 for UC. A significant association was found with dying in the possible and very likely sepsis group than in the unlikely.