Search In this Thesis
   Search In this Thesis  
العنوان
Analytical study on some drugs affecting smooth and/or skeletal muscles
المؤلف
Dina Abbas Ahmed Elmously
هيئة الاعداد
باحث / Dina Abbas Ahmed EL Mously
مشرف / Nadia Mohamed Mostafa
مشرف / Nagiba Yehia Mohamed Hassan
مشرف / Ghada Mostafa El-Sayed
الموضوع
Analytical chemistry
تاريخ النشر
2022.
عدد الصفحات
244 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
صيدلة
تاريخ الإجازة
1/1/2022
مكان الإجازة
جامعة القاهرة - كلية الصيدلة - Pharmaceutical sciences “Analytical chemistry”
الفهرس
Only 14 pages are availabe for public view

from 244

from 244

Abstract

This thesis is concerned with the analysis of some drugs affecting smooth and/or skeletal muscles. It comprises two parts:
Part I is a general introduction and literature review on Neostigmine methylsulfate as well as descriptions of various analytical methodologies for determining Neostigmine methylsulfate, 3-hydroxyphenyltrimethyl ammonium methylsulfate, and 3-dimethylaminophenol as its impurities in the presence of citric acid as a dosage form additive.
Part II contains literature review of Amlodipine besylate and Irbesartan in addition to several analytical methodologies that were described for analyzing the binary mixture.
The introduced methods include chromatography, chemometrics, capillary electrophoresis, spectrophotometry and electrochemical methods. They are characterized by their reproducibility and adequate degree of sensitivity for the assay of the cited drugs in their pure powdered form and marketed formulations