الفهرس 
Comparative study between long pulsed Nd: YAG laser alone versus its combination with Eflornithine for the treatment of Pseudofolliculitis barbae
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Abstract
Pseudofolliculitis barbae (PFB) is a chronic inflammatory disorder occurring
mostly in regions of thick hair growth after shaving. PFB is characterized clinically by multiple
painful, pruritic erythematous papules and, less commonly, pustules, nodules, or abscesses.
Aim: To evaluate the efficacy of topical Eflornithine cream only, long-pulsed Nd-YAG laser,
versus their combination for PFB management.
Patients and Methods: Overall, male patients with PFB were allocated into three treatment
groups; group (n= ): Treated by topical Eflornithine cream twice daily for weeks, group
II (n= ): Treated by Long-pulsed Nd-YAG laser for sessions weeks’ interval, group III
(n= ): Treated by their combination for weeks. These patients were evaluated after weeks
and for a further weeks through serial photographs, Folliscopic evaluation, and a quartile
grading system for improvement.
Results: After weeks of treatments, the mean improvement percentages of the inflammatory
papules, as well as hair density in the Long-pulsed Nd-YAG laser + Eflornithine cream, treated
group was significantly higher compared with either Eflornithine cream treated group or laser
only treated group. The same relationship was demonstrated after weeks of follow-up but
with lower improvements compared with weeks of treatment outcome.
Conclusions: Topical Eflornithine cream exerts an additive effect on long-pulsed Nd-YAG laser
in enhancing the rate and degree of hair reduction and inflammatory papules in PFB cases with a
further follow-up improvement. This combined approach should be long-established in larger
sample sizes and long-term studies.