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Abstract
The aim of the present study is to investigate the effect of EMR (frequency 900 MHz modulated at 217 Hz, power density 0.02 mW/cm2 , SAR 1.245 W/kg) on malondialdehyde, nitric oxide, catalase, reduced glutathione, glutathione reductase and superoxide dismutase in the hippocampus, cortex, striatum and hypothalamus of adult rats. This study also extends to evaluate the therapeutic effect of green tea extract (150 mg/kg) on the previous mentioned parameters in animals exposed to EMR after exposure and during EMR exposure. Disturbances in oxidant and antioxidant parameters were recorded in the selected brain areas after EMR exposure. These disturbances suggest that a state of oxidative stress may occur in the brain after EMR, being more prominent in the hippocampus and striatum. Co-administration of green tea extract at the beginning of EMR exposure for 2 and 3 months in the studied brain areas has a more beneficial effect against EMR-induced oxidative stress than oral administration of green tea extract after exposure was started