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Abstract This study has been demonstrated that dexmedetomidine is an efficacious and safe adjuvant in general anaesthesia.The scope of spinal surgery is considerable. Both adult and pediatric patients present for surgery, which may be elective or urgent. They mainly present with one of five pathologies: trauma, infection, malignancy, congenital/idiopathic or degenerative disease. Surgery may be required at any site in the spine from cervical to lumbosacral. They mainly present with one of five pathologies: trauma, infection, malignancy, congenital/idiopathic or degenerative disease. Surgery may be required at any site in the spine from cervical to lumbosacral. Procedures range from minimally invasive microdiscectomy, to prolonged operations involving multiple spinal levels and significant blood loss |