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Abstract
The study was designed to detect the effect of handgrip exercise training on the brachial artery adaptation in patients with type 2 diabetes mellitus. Methods: the study was carried out on forty type 2 diabetic patients (20 men and 20women) for (10-15years). Their age ranged from (45 to 55) years. Patients were selected from the outpatient clinic of El- Agouza Police Authority Hospital in the period from April 2013 to June 2014. A Doppler ultrasound was used to assess the brachial artery adaptation (the brachial artery diameter, blood velocity and shear rate) before and after the period of study (8 weeks). Patients were assigned into 2 equal groups in number. group (A) received unilateral isometric handgrip exercise 22 min per session, 3 sessions per week for 8 weeks and group (B) received aerobic exercise in form of walking on electronic treadmill for 30 min, 3 sessions per week for 8 weeks. Results: group (A) showed significant improvement in brachial artery adaptation as increased brachial artery diameter by 3.42%, brachial artery blood velocity by 21.62% and shear rate by 17.22% compared with the group (B) which shows no significant increase in brachial artery diameter by 0.47%, brachial artery blood velocity by 2.73%and shear rate by1.48%.Men showed statistical significant more than women in brachial artery diameter, blood velocity and shear rate. Conclusion: Isometric handgrip exercise improved brachial artery diameter, blood velocity and shear rate in patients with type 2 diabetes