الفهرس 
Title : The Effect of Culture System on Embryonic Development and Aneuploidy Rate in ICSI Cases
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Abstract
Patients undergoing ICSI or IVF cycles often suffer from recurrent
implantation failure (RIF). To ensure live birth and embryonic
viability, culture systems should be optimized in all ICSI and IVF
cycles. The success of IVF can be affected by the culture systems
employed for embryonic development. It has been argued that
covering microdrops with oil in culture systems can prevent
microbial infection, ensure suitable osmotic and pH conditions, and
prevent the evaporation of the medium. Comparing the embryological
and clinical outcome of using GPS dishes covered with paraffin oil
and SPL dished with mineral oil for patients with previous RIF. The
study was a prospective randomized controlled trial and the sample
size consisted of 174 patients undergoing ICSI cycles at a private
fertility center during the period between April 2017 and March
2020. Patients’ embryos were randomly assigned into one of the two
of the aforementioned groups. The two groups weren’t statistically
significantly different in male age, female age, collected oocyte
number, number of mature oocytes, and number of blastocysts
undergoing PGD-A. For the pre-implantation parameters of the
embryos, fertilization, cleavage, and high-quality blastocyst rates
were statistically significantly higher in the GPS dishes with paraffin
oil group than in the SPL dishes covered with mineral oil group
(77.5, 80.1, and 79.45%) (p = 0.012, and 0.001). We conclude that
embryonic development can be enhanced by using GPS dishes with
paraffin oil overlying.