الفهرس 
Anaemia of prematurityOnly 14 pages are availabe for public view
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Abstract
Anaemia of prematurity is a pathological condition unlike physiologic anaemia in newborns. The pronounced decline in the haemoglobin (Hb) concentration that occurs in ELBW infants is usually associated with abnormal clinical signs and requires allogeneic RBC transfusions. AOP is characterized by reduced endogenous erythropoietin (EPO), reduced RBC lifespan and hyporegenerative bone marrow. Non-physiologic factors related to prematurity, such as phlebotomy losses for laboratory evaluations and nosocomial infections resulting in oxidative haemolysis, also contribute to high transfusion preterm infants (Alan and Arsan 2015).
The aim of this work was to determine the serum levels of erythroferrone and their relation to the anaemia of prematurity.
This study was case control study carried out in the the Pediatric Department, Faculty of Medicine, Menoufia University.
This study included two groups;
group A: included all newborns at all ages and both sexes with anemia of prematurity fulfilling all inclusion and exclusion criteria admitted to the NICU during the study period.
group B: included group of healthy newborns.
All participants were subjected to history taking, general examination, Local examination, Abdominal examination and Laboratory investigations including complete blood count (CBC), and blood film, C reactive protein (CRP), Blood culture when needed, Kidney functions tests: including serum creatinine and urea, Liver function tests: including serum aspartate aminotransferase (AST) and alanine aminotransferase (ALT), Serum sodium (Na) and serum potassium (K), Serum Hepcidin level, erythroferrone and hepcidin analyzed using ELIZA kits.