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العنوان
Anti - diabetic anti - oxidant effect of hibiscus sabdariffa L. extract on the submandibular salivary gland of alloxan-induced diabetic albino rats :
الناشر
Nermeen Mohamed AbuBakr Mohamed Tawfik ,
المؤلف
Nermeen Mohamed AbuBakr Mohamed Tawfik
هيئة الاعداد
باحث / Nermeen Mohamed AbuBakr Mohamed Tawfik
مشرف / Nahed Abdelsalam Khalil
مشرف / Zainab Amin Ibrahim
مناقش / Nermeen Mohamed AbuBakr Mohamed Tawfik
تاريخ النشر
2014
عدد الصفحات
183 Leaves :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
Dentistry (miscellaneous)
تاريخ الإجازة
21/3/2015
مكان الإجازة
جامعة القاهرة - الفم والأسنان - Oral Biology
الفهرس
Only 14 pages are availabe for public view

from 213

from 213

Abstract

Hibiscus sabdariffa linn. (HSL) is an annual herbaceous shrub belonging to the family malvaceae. It is well established that the plant contains a variety of bioactive compounds such as anthocyanins and phenolic compounds. Studies have shown that these biologically active compounds have: anti - oxidant, anti - diabetic, anti - hypercholesterolemic, anthelmintic, anti - hyperlipidemic, cardioprotective, anti - inflammatory, hypotensive and anti-viral properties. This study aimed to investigate the anti - diabetic anti-oxidant effect of HSL extract on the histological structures of the submandibular salivary gland in normal and alloxan - induced diabetic albino rats with immunohistochemical localization of NFmB and iNOS in the same tissue under investigation and through measuring blood glucose levels. A total of 50 adult male albino rats were used and divided into 5 groups (10 rats each). group Ї was the control group. group ЇЇ was given a daily dose of HSL hydro - alcoholic extract orally for 4 weeks. group ЇЇЇ was given a single intraperitoneal injection of 150 mg/kg body weight alloxan monohydrate to induce diabete