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العنوان
MN1 and PTEN gene expression in acute myeloid leukemia /
الناشر
Mohamed Abdelmohsen Zaki Mostafa ,
المؤلف
Mohamed Abdelmohsen Zaki Mostafa
هيئة الاعداد
باحث / Mohamed Abdelmohsen Zaki Mostafa
مشرف / Rania Ahmed Zayed
مشرف / Maha Abdelhameed Eltaweel
مشرف / Shahira Kamal Anis
تاريخ النشر
2014
عدد الصفحات
134 P. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
علم الأورام
تاريخ الإجازة
7/4/2015
مكان الإجازة
جامعة القاهرة - كلية الطب - Clinical and Chemical Pathology
الفهرس
Only 14 pages are availabe for public view

from 149

from 149

Abstract

Background: AML is a heterogeneous disease in clinical character and molecular genetics, we can detect many kinds of abnormal expression of genes. Among them, meningioma 1 (MN1) high expression and phosphatase and tensin homolog (PTEN) low expression are thought to be correlative with incidence of leukemia. Aim of the study: The aim of this study is to determine the expression and prognostic impact of MN1 and PTEN mRNA in AML cells by Real time Reverse Transcription-PCR and to correlate the their expression with other clinical and laboratory prognostic factors