Search In this Thesis
   Search In this Thesis  
العنوان
Evaluation of the effect of incretin enhancer on improving nerve conduction velocity in diabetic male rats /
الناشر
Lamiaa Mohamed Mahmoud Ibrahim ,
المؤلف
Lamiaa Mohamed Mahmoud Ibrahim
هيئة الاعداد
باحث / Lamiaa Mohamed Mahmoud Ibrahim
مشرف / Ibrahim Mohammady
مشرف / Samah El-Attar
مشرف / Hani Ei-Sebaii
تاريخ النشر
2014
عدد الصفحات
197 P. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب (متفرقات)
تاريخ الإجازة
1/1/2014
مكان الإجازة
جامعة القاهرة - كلية الطب - Physiology
الفهرس
Only 14 pages are availabe for public view

from 226

from 226

Abstract

Background: Diabetes has become a widespread epidemic, primarily because of the increasing prevalence and incidence of type 2 diabetes. Diabetic polyneuropathy (DPN) is the most common chronic complication of diabetes. Incretin hormones promote stimulation of insulin secretion, inhibition of glucagon secretion, and they are directly neurotrophic. It was found that DPPI treatment improved motor and to a lesser extent sensory nerve conduction velocity. Objective: This study tried to evaluate the effects of incretin enhancer (DPPI: sitagliptin) given orally for streptozotocin induced diabetic peripheral neuropathy (DPN) in type II diabetic male rats