الفهرس 
Cardiovascular effects of propofol and midazolam after coronary artery ligation in rats
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Abstract
Over the years, several theories have been advanced to explain the process of atherosclerosis. None of these is able to account for all aspects of the disease. The most recent, which views atherosclerosis as a consequence of inflammation in the vessel wall, is supported by the results of large-scale clinical trials. Under anesthesia with intraperitoneal sodium pentobarbital male albino rats were divided into 5 groups ; control group, sham operated group underwent 30 minutes left anterior descending coronary artery ligation, propofol-treated group, midazolam-treated group and propofol and midazolam group. In propofol-treated group marked reduction of ventricular arrhythmia observed; in midazolam-treated group moderate reduction of ventricular arrhythmia observed. Propofol and midazolam have differential effects on ischemia-induced arrhythmias via modulation of the autonomic nervous system and/or a principal gap-junction protein, Cx43