الفهرس Only 14 pages are availabe for public view
 |  | from | 183 |  |  |
| | | from | 183 | | |
Abstract
Background: Diabetes mellitus is a clinical syndrome characterized by hyperglycemia caused by relative or absolute deficiency of insulin in the body. Painful neuropathy is common in the diabetic population, affecting approximately 50% of patients with chronic diabetes. Although painful neuropathy responds to antidepressants, anticonvulsants and opioid agonists, these drugs proved to have different side effects and sometimes not effective. Hence, we need to seek safe, non-invasive and effective therapeutic options. Trans-cranial magnetic stimulation (TMS) is a non- invasive mechanism used in relieving neuropathic pain.TMS pulses when applied repetitively they can modulate cortical plasticity, consequently causing excitability or inhibition according to the rate of stimulation.