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Abstract
Background: The optimal temperature of cardioplegia solution in patients undergoing mitral valve surgery is still debatable. Objective: To compare between warm and cold cardioplegia in patients undergoing mitral valve surgery. Patient and Methods: A prospective comparative study on 100 patients undergoing mitral valve replacment surgery. Patients were divided into two groups; ( warm group, used antegrade warm blood cardioplegia n = 50) and (cold group, used antegrade cold blood cardioplegia n = 50). Biomarkers of cardiac injuery, operative and clinical data were collected. Results: The need for DC shock , initial dose and duration of inotropes , total drainage and the serum troponin , LDH levels were lower in the warm group by highly significant statistically values (p value<0.01). The serum level of CK and CK-MB were less in the warm group by statistically significant values (p value<0.05). The serum creatinine level , total bypass time , time to regain consciousness, time for extubation and incidence of wound infection were less in the warm group by insignificant statistically values (p value>0.05).