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Abstract The breast cancer is the most common malignant tumor among women. is early detection and proper diagnosis, which has its major impact on further management and prognosis. US has been established as a complementary tool for mammography because of long experience with its use, accessibility, relatively low cost and the opportunity it affords for real time guidance of aspiration or needle biopsy. However, its operator dependence nature remains its main limitation.The current study was conducted at Kasr Elaini hospital with 30 patients including 36 breast lesions to correlate the results of DWI - MRI and the calculated ADC value with the DCE - MR mammography to determine the specificity of DWI in detection and diagnosis of breast lesions, by reach a cut off value for differentiating malignant and benign lesion, and investigate the possibility of DWI-MRI replace the contrast imaging. Cases were referred from general surgery departments in Kasr Elaini hospital |