الفهرس 
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Abstract
This study was carried out through the cooperation protocol between the Animal and Fish Production Department, Faculty of Agriculture, Alexandria University and the National Institute of Oceanography and Fisheries (NIOF) Baltim, Kafr El Sheik Governorate in summer of 2021. The experiment was designed to investigate and to evaluate the effects of dietary Bile Acids (BA) supplementation as feed additives at 0, 0.25, 0.50, 0.75, 1.0, 1.25 and 1.5 g BA /kg diet for 70 days on growth performance, nutrient utilization, body composition, non-specific immune response, antioxidant assay, intestinal microbiota, gene expression in liver tissues, peritoneal fat, musculature, liver, and their intestinal morphology of striped catfish Pangasius hypophthalmus, known in Arabic(Basa fish). Apparently healthy 210 striped catfish Pangasius haypophthlamus fingerlings with an average initial body weight of 10.30 ± 0.20 g /fish. Twenty-one Habbas with size of 70 ×50×70 cm, in seven treatments with triplicates of each one. Fish were distributed at an initial stocking density of 10 striped catfish fingerlings / haba that were weighed, and their weight was recorded biweekly. Seven diets with 30 % crude protein were supposed to be used in the trial, the first diet it is a control diet (D1), without BA (0.0), while D2 to D7 were supplemented with 0.25, 0.50, 0.75, 1.0, 1.25 and 1.5 g BA /kg diet, respectively. Fish were hand-fed with the experimental diets twice daily for 70 days (six days a week) at a rate of 6 % of body weight fish biomass for the first 30 days then decreased to 3 % for the rest of the experimental period.
The results of the present study are summarized as following: 6.1.1. Chemical analysis of the experimental diets used in the present studyvalues 7.77, total ammonia values 0.03 mg/L dissolved oxygen was with average 5.36 mg/L suggesting that these values are suitable for rearing Striped catfish.6.1.3. Growth performance and survival rate (%)
The growth performance parameters values increased significantly (p < .05) with the
increasing dietary BA supplementation from 0.25 to 1.25g/kg diet and then decreased
significantly in the fish fed 1.50g BA /kg diet. According to the results of the experiment;
it can be said that the highest values of the growth performance were for those fish fed on diet No. (6) containing 1.25g BA /kg diet, followed by the fish fed on diets 1.2.3,4 and 5, respectively and there were statistically significant differences between all treatments (P <0.05).Total weight gain, average daily gain , and specific growth rate of striped catfish fingerlings fed on diet No.6 were (34.80g / fish, 0.36g / fish / day, 1.79 %/day ), respectively and compared by control diet (12.56g / fish, 0.17g / fish /day, 1.12%/day ), respectively and there were statistically significant difference between all treatments (P 0.05).