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العنوان
Lipoprotein (a) and Circulating Monocyte Subsets In Patients With Coronary Atherosclerosis And Their Relation To Disease Severity /
المؤلف
Abdelshafy, Yasmen Mohamed ELsherif.
هيئة الاعداد
باحث / ياسمين محمد الشريف عبد الشافي
مشرف / عماد علام عبد النعيم
مشرف / نجلاء مكرم فرج
مشرف / أسماء خلف الله كامل
الموضوع
Diagnosis, Laboratory. Clinical Pathology.
تاريخ النشر
2023.
عدد الصفحات
112 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
أمراض الدم
تاريخ الإجازة
22/6/2023
مكان الإجازة
جامعة المنيا - كلية الطب - الباثولوجيا الإكلينيكية
الفهرس
Only 14 pages are availabe for public view

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from 133

Abstract

The aim of this study is to assess the impact of high lipoprotein (a) on severity of coronary atherosclerosis, evaluate the prevalence of different monocyte subsets in coronary atherosclerotic patients and their relation to disease severity and to correlate lipoprotein (a) level with different monocyte subsets in coronary atherosclerotic patients.
The results of the study were summarized as follow:
There was no statistically significant difference regarding sex and age distributions in the two groups.
Platelet count showed statistically significant increase in severe atherosclerotic subgroup when compared to mild and moderate subgroups.
Patients with atherosclerosis showed statistically significant elevation in serum creatinine and blood urea levels when compared with control group.
Patients with atherosclerosis showed statistically significant lower albumin levels than control group.
Patients with atherosclerosis showed statistically significant higher triglycerides levels and statistically significant lower HDL levels than control group.
Patients with atherosclerosis showed statistically significant higher values CRP than control group.
Patients with atherosclerosis showed statistically significant higher Lp (a) levels than control group.
There was no significant difference between mild, moderate and severe subgroups regarding LP (a) level.
There was statistically significant elevation in monocytic count in the patient group when compared to the control group.
Monocyte count and percentage were increased in severe atherosclerotic subgroup when compared with mild and moderate subgroups and this was statistically significant.
Patients with atherosclerosis showed statistically significant elevated proportion and absolute count regards intermediate and non classical monocytes subsets when compared to control group, while classical monocyte subset was significantly higher in control group when compared with the atherosclerotic group.
There was statistically significant difference in monocyte subsets percentage between mild, moderate and severe atherosclerotic patients.