الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
The aim of this study was to evaluate corneal endothelial cell changes in patients undergoing Pars plana vitrectomy with either silicon oil or SF6 gas tamponade.
This study included 50 eyes of 50 patients, 24 males and 26 females. Mean age ± SD was 50.32 ±15.28 years.
Patients were divided into two groups according to the used tamponade; each group of them included 25 eyes.
group I: patients who were operated for PPV with SO injection.
group II: patients who were operated for PPV with SF6 gas injection.
Inclusion criteria included patients with clear cornea, no silicone oil in the anterior chamber, normal IOP and lens status: phakic or psedophakic.
Exclusion criteria included patients with coexisting corneal pathologies, an endothelial cell count of fewer than 1500 cells/mm2preoperatively, glaucoma, uveitis, trauma and previous refractive surgery.
Preoperatively, complete ophthalmic examinations were performed to all patients including the following: history, visual acuity, slit lamp examination, IOP measurement, fundus examination and imaging of the corneal endothelium by noncontact specular microscope (Tomey EM-3000, Nishi-ku, Nagoya, Japan) to assess [endothelial cell density (ECD), central corneal thickness (CCT), Coefficient of Variation (CV) and Hexagonal cells (HEX)].
23-gauge pars plana vitrectomy (PPV) was done depending on the reason for the vitrectomy with tamponade silicone oil (silicone 1000 cs) in group I and SF6 gas in group II.
Regular postoperative follow-up was conducted on 1stmonth,and 3rd month with special attention to slit-lamp examination (corneal state), IOP, visual acuity and imaging of corneal endothelium by Tomey EM-3000 non contact specular microscope for assessment of endothelial cell parameters mentioned before.
There was no statistically significant difference between the 2 groups as regard age and sex.
There was a statistically significant difference between the two groups as regard preoperative mean endothelial cell density by mere coincidance. There was a statistically significant difference between the two groups as regard percent reduction in endothelial cell density over the 3-month follow up period with more reduction in silicone oil group. EC loss over the 3-months follow-up period was statistically significant in phakic and pseudophakic patients with more reduction in pseudophakic group.
There was no statistically significant difference between the 2 groups as regard co-efficient of variation and hexagonality over the 3-month follow up period.
There was no statistically significant difference between the 2 groups as regard central corneal thickness over the 3-month follow up period.