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العنوان
Effect of Terminalia chebula Fruit on Biological, Biochemical and Histopathological Changes of Induced Obese Rats /
المؤلف
Abdallah, Heba Nabil Ebrahim.
هيئة الاعداد
باحث / هبه نبيل ابراهيم عبد الله
مشرف / عماد محمد عبد الحليم الخولى
مشرف / عبير نزيه احمد
مناقش / لمياء محمود لطفى الصادق
مناقش / بسمة رمضان خطيب
الموضوع
nutrition.
تاريخ النشر
2023.
عدد الصفحات
139 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
اقتصاد منزلي
تاريخ الإجازة
25/8/2023
مكان الإجازة
جامعة المنوفية - كلية الإقتصاد المنزلى - التغذية وعلوم الاطعمة
الفهرس
Only 14 pages are availabe for public view

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from 169

Abstract

The goal of this study is to find out how the Effect of fruit powder and extract of Terminalia chebula on overweight rat’s obesity. Six groups, (6 for each one), had been formed from the 36 male albino rats, every weighing 160±10g. Rats have been given a high-fat diet (20% sheep fat) to assist them increase weight. The study assessed lipid fractions which includes triglycerides (TG), total cholesterol (TC), high-density lipoprotein (HDL), low-density lipoprotein (LDL), very low-density lipoprotein (VLDL), glucose levels and liver enzymes that is Alanine amino transferase (ALT), Aspartate amino transferase (AST), & alkaline phosphatase (ALP) as well as renal biomarkers (creatinine, uric acid, and urea), red blood cells,white blood cells,platelet and Hemoglobin.Also,Liver and Heart examined Histopathological. The chemical composition, total phenols, and total flavonoids were also estimated and phenolic compounds were identified using a high-performance gas chromatograph. The result confirmed that, when rats fed Terminallia chebula fruit extract, the treated groups showed considerably reduced glucose levels, liver enzymes, and renal biomarkers. In addition, lowest lipid fractions, such as TC, TG, LDL and VLDL levels had been observed and vice versa for HDL levels. The chemical composition results showed that Terminalia chebula contains many phenolic compounds and antioxidants. As conclusion, overweight rats have been fed an extract of Terminalia chebula fruit at a level of 500 mg/kg, displayed improving lipid profiles, glucose, liver enzymes and renal function ranges. As a result, the research advises using Terminalia chebula fruit in the recommended meal and drinks for decreasing body fat percentages.