الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Cancer can be caused by a mix of genetic predisposition, environmental agents and lifestyle. Age and breast density are naturally occurring factors that could increase the risk of developing the disease. In addition, it is well known that changes in the circadian rhythm, augment the probability of having breast cancer. A recent study on a primary tumor sample from a small population has underscored the association of single nucleotide polymorphisms (SNPs) in circadian genes associated with increased risk for breast carcinoma. SNPs of core circadian genes including BMAL1 (rs2279287) significantly influence the gene expressions based on their location on the gene