الفهرس 
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Abstract
Crohn’s disease (CD) is one of the gastrointestinal autoimmune diseases which includes crohns disease and ulcerative colitis.
Crohn’s diseases affects the whole layers of the GI tract causing trans mural inflammation making it more liable for complications like strictures, abscesses, and fistulisation .unlike UC which only causes superficial mucosal lesions.
Some cases were found to not be compactable with neither CD nor UC, and histopathologists called it indeterminate colitis.
Small intestinal affection of crohn’s disease was difficult and was held only before by barium follow through or capsule endoscopy which had its limits.
For the early detection of superficial lesions like erosions and tiny ulcers, DBE is more effective than radiographic exams. Additionally, it offers a thorough description of the location and morphology of lesions and surrounding mucosa (such as cobblestone appearance and edema), which aids in distinguishing CD from other possible diagnoses. DBE is also helpful for offering therapeutic procedures like balloon dilatation.
This study is designed to help with the diagnosis of isolated small bowel CD and assess the relation between proximal small intestinal affection and clinical assessment like the Harvey Bradshaw index and laboratory results like fecal calprotectin and CRP.
The study is done on 50 cases previously diagnosed as Crohn’s based on clinical, laboratory,laboratory radiological, endoscopic, and histopathological bases.
Exclusion criteria were history of myocardial infarction, stroke,stroke pregnancy, patients on biological therapy, and advanced liver and kidney diseases.
The mean age in the current study was 37.013.77 years. Females made up 22 (44.0%) and males 28 (56.0%). A mean body weight of 76.54 16.09 kg was recorded. The mean values for heart rate, systolic blood pressure, and diastolic blood pressure were 87.70 9.72, 115.5 21.39, and 77.60 10.41, respectively. Harvey-Bradshaw Index on average was 13.56 6.84. The average ESR was 63.60, the average CRP was 28.56, the average calprotectin was 411.0, the average urea was 29.40, and the average creatinine was 1.05, respectively.