الفهرس 
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Abstract
This multicenter, prospective cohort research was carried out at three distinct health facilities within the MINYA Governorate. Data were obtained from 1000 individuals with laboratory-proven COVID-19 infection; all patients were medically sick enough to warrant hospitalization and had SARS-CoV-2 infection confirmed by positive polymerase chain reaction testing of a nasopharyngeal sample.
Data were obtained prospectively from patients’ medical files in a consistent way. At baseline (i.e., hospital admission), we examined demographic and epidemiological factors, comorbidity profile, clinical presentation, laboratory, chest computed tomography (CT) scan, and echocardiography data. Routine blood tests included a full blood count, kidney and liver function tests, creatine kinase, C-reactive protein (CRP), procalcitonin, D-dimer, ferritin, and interleukin-6 (IL-6). The CT scan imaging findings were supplied based on the primary pattern of lesions and the magnitude of the lesions. The initial therapies administered as well as the clinical course of the hospitalization were recorded.
The study’s goal was to evaluate the relationship between risk factors like the elderly, hypertension, diabetes, COPD, CKD, and the severity of corona virus disease, the incidence of AKI at ICU admission as defined by the KDIGO scoring system, the significant association of AKI, ARDS, and IMV with mortality rates for COVID-19 ICU patients, the incidence of thrombotic complications in COVID-19 ICU patients, and to analyze the discharge rate and
In terms of age, gender, tiredness, diabetes, bronchial asthma, AKI, and HTN, our present research discovered a statistically significant difference between the analyzed groups (P value 0.05). The differences in smoking, cough, sore throat, headache, fever, diarrhea, COPD, CKD, and hepatic impairment were not statistically significant (P value >0.05).
AKI was found in 301 (30.3%) of the patients, whereas 694 (69.7%) did not have it. KDIGO stage I was discovered in 155 (51.5%) patients, stage II in 69 (22.9%) patients, and stage III in 77 (25.6%) individuals.
Non-invasive mechanical ventilation was utilized in 493 (49.5%) instances, whereas invasive mechanical ventilation was used in 155 (15.6%) patients. The mean SD of O2 saturation on admission was 67.815 with a range of (22-92), the mean SD of p/f ratio was 200.669 with a range of (53.8 - 320), and 842 (84.6%) patients improved with a mortality rate of (15.4%).
There was statistical significance in terms of PE and DVT between the groups examined (p value 0.05).