الفهرس | Only 14 pages are availabe for public view |
Abstract Preeclampsia is a pregnancy condition marked by new-onset hypertension that most usually manifests after 20 weeks of pregnancy and frequently close to term, with or without proteinuria, organ damage, or uteroplacental dysfunction. Preeclampsia can be described as a pregnancy-specific syndrome which cause widespread vasospasm and vascular endothelial dysfunction Pregnancy is associated with physiologic hyperlipidemia, and in a healthy pregnancy, this characteristic—which is thought to be regulated by hormones—is not atherogenic. Lipid metabolic abnormalities have been identified as possible risk factors for the onset and advancement of preeclampsia. The goal of the study is to judge the connection between the beginning of preeclampsia and an aberrant lipid profile in the early second trimester, between weeks 14 and 16. The patients were drafted from El-Shatby Maternity University Hospital. The current study built-in 260 pregnant women between 14th to 16th weeks of gestations attending the antenatal clinic and undergoing their screening for developing preeclampsia during their pregnancy, after measurement of TC, TG, HDL-C, LDL-C between 14th to 16th weeks of gestations. Further subcategorized into four groups based on the results of lipid profile, group A (61 cases) normal lipid profile &non preeclampsia, group B (9 cases) normal lipid profile in addition to preeclampsia, group C (146 cases) abnormal lipid profile plus non preeclampsia,group D(44 cases) abnormal lipid profile and preeclampsia. The result showed that women with abnormal lipid profile have higher risk to develop preeclampsia, Abnormal levels of TC,TG, LDL may contribute in the promotion of hypertension in pregnant women. |