الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Sedation is an important part of therapy in mechanically ventilated patients in the intensive care unit. Delayed gastric emptying is a common complication of sedation in critically ill patients that may lead to gastrointestinal intolerance which can increase risk of reflux and aspiration. Midazolam is a Y-aminobutyric acid (GABA) receptor agonist. It has been one of the most commonly used sedative drugs in ICU. Dexmedetomidine is a selective α2-adrenoceptor agonist which can be used in anaesthesia and ICU. It provides proper sedation and has also analgesic and amnesic effect. It has no respiratory depression action. It`s now established as novel approach to intensive care sedation. Residual gastric volume measurement has been recommended to monitor tolerance to enteral nutrition in mechanically ventilated patients. The traditional method of recurrent gastric suctioning has been associated with interruption of enteral feeding and loss of calories. Gastric ultrasound is a simple, non-invasive, bedside method that can be used easily to detect gastric contents. This based on qualitative examination of gastric antrum. This Prospective randomized controlled double-blind study was conducted on 90 patients in the ICU of Tanta university Hospitals. Our study aimed to compare the effect of midazolam and dexmedetomidine on gastric emptying using gastric ultrasound for assessment of cross-sectional area of gastric antrum in mechanically ventilated patients receiving enteral nutrition.