الفهرس | Only 14 pages are availabe for public view |
Abstract Aim: Evaluate the effect of the addition of Ag nanoparticles on the antibacterial activity, solubility and ions release of compomer restorative material at different time interval. Methodology: 0.025 ml nanosilver alcohol solution (5000 ppm) was manually mixed with 2g of Composan glass (compomer material). Composan glass without nanosilver was used as the control. A total of 48 disc shaped samples were prepared (24 from each group) with dimensions of 15 x 1 mm and immersed in distilled water for 24 h, 1 month and 3 months. After each time interval, 24 discs (4 in each group at each immersion time) were assessed for antibacterial activity by the agar diffusion test using Streptococcus mutans. For water sorption and solubility, 24 discs (12 in each group) were evaluated by means of weighting the samples before and after water immersion. The fluoride release from the samples in ppm was measured by using a fluoride ion selective electrode. The silver ion released in ppm was determined using inductively coupled plasma mass spectrometer. Results: The experimental group showed significantly higher inhibition zone values for all the follow up results in comparison to the control group. For water sorption test, the higher values were detected in the experimental group after 1 month and 3 months. While for the solubility the higher values were detected in the experimental group after all the follow ups. Regarding the fluoride ion release, comparison between both groups showed that there was no significant difference after all follow ups (P<0.05). For the silver ion release, the results showed significant difference regarding all follow up with higher release values detected in the experimental group. Conclusions: Composan glass incorporated with 0.025 ml Ag nanoparticles is promising antibacterial restoration against Streptococcus mutans Key words: compomer,silver nanoparticles,antibacterial activity,solubility,fluoride, release, silver release. |