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Abstract The success of embryo implantation and the course of pregnancy are fundamentally dependent on endometrial receptivity. While measuring endometrial thickness change One non-invasive measure of endometrial receptivity that has been proposed to predict pregnancy outcomes in IVF cycles is the duration between the end of the estrogen phase and the embryo transfer; this marker is regarded to be more relevant.. The goal of the current observational cohort study was to determine how the rate of pregnancy following frozen embryo transfer was affected by changes in endometrial thickness, or endometrial compaction, following progesterone administration. The study covered 317 women who underwent frozen embryo transfer following hormonal preparation and ran from May 2022 to June 2023.Patients were split into two groups: the compacted group and the non-compacted group, based on the change in endometrial thickness following the addition of progesterone. Regarding the study’s main finding, the data revealed that the patients in the compacted group had a substantially greater pregnancy rate than the patients in the non-compacted group. The compacted group had a significantly higher chemical pregnancy rate (68.6% vs. 46.2%) P=<0.001), compared to the non-compacted group. Furthermore, comparing the compacted and non-compacted groups, there was a significant difference in the clinical pregnancy rate (61.9% vs. 42.5%; P=<0.001) and the continuing pregnancy rate (57.1% vs. 40.6%).. (P<0.005). We came to the conclusion that endometrial compaction significantly affects the rate of FET pregnancy and affects endometrial receptivity. |