الفهرس 
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Abstract
Acne is the most prevalent skin condition, affecting about 85% of the population aged 11 to 30 years old .It is not a life threatening condition, yet it lasts for years. Acne resolves completely without major sequelae in most patients, but in a few, it may leave behind disfiguring scarring or hyperpigmentation
The pathogenetic factors that influence the development of acne include sebaceous gland hyperplasia with seborrhea, ductal hypercornification, Propionibacterium acnes colonization of the follicle and inflammation
Topical and oral medications, such as retinoids, benzoyl peroxide, macrolide antibiotics, and isotretinoin, are the mainstay of treatment for acne. Despite these therapies, there remains the need for additional safe , efficacious treatment options. Treatment alternatives suggested include chemical peeling, microdermabrasion, radiofrequency, laser, and photodynamic therapy
Studies on chemical peels in acne showed generally favourable results despite differences in assessments, treatment regimens and patient populations. It is suggested that superficial chemical peeling hasten the transition of closed comedones to the surface of epidermis resulting in a quicker clearance of the lesions. The intensity of the effect depends on the PH and concentration of substance used. Glycolic acid and salicylic acid are the most commonly used chemical peels in acne but there have been relatively few clinical trials using other peels Although microdermabrasion is a widely used rejeuvenation procedure, few studies have studied its role in acne. Lioyid, (2001) reported its efficacy with excellent results in 38% of acne patients, while others reported that it’s a mild treatment that had to be combined with other lines of acne therapy
suggested that the combination of Microdermabrasion and chemical peels should maximize the benefits of both therapies, with minimal down time for the patient.the combination should enhance the penetration of both therapies as they both decrease the thickness of the stratum corneum. While reported improvement in comedonal and inflammatory acne lesions with combined therapy of Microdermabrasion and chemical peeling with glycolic or salicylic acid.