الفهرس 
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Abstract
Anogenital warts are a nonmalignant skin neoplasm caused by the human papillomavirus (HPV). HPV is the most common viral infection of the reproductive tract is the cause of a range of conditions, including precancerous lesions that may progress to cancer.
The treatment of warts poses a therapeutic challenge for physicians. No single therapy had been proven effective at achieving complete remission in every patient. As a result, many different approaches to wart therapy exist. These approaches include chemotherapy by (salicylic acid, trichloroacetic acid, formaldehyde, glutaraldehyde, formic acid, cantharidin, 5-fluorouracil, bleomycin, podophyllin, podophyllotoxin, silver nitrates and retinoids), cryotherapy mostly by liquid nitrogen, electrosurgery (curettage and cautery), laser therapy and photodynamic therapy. Each mode of therapy has its own complications and failure rates.
Bleomycin has the advantage over traditional treatments as it acts by inhibiting DNA synthesis in cells and viruses; it induces strand cleavage of the DNA molecule, however most physicians and patients refuse it because of the pain during intralesional injection. Microneedling overcomes this point by easily delivering of bleomycin with toularable pain.
Therefore we designed this study to compare between microneedling assisted topical bleomycin and cryotherapy in treatment of AGWs.
The study included 40 Patients divided into two groups (A&B). Each group consists of (20) patients. group (A) were treated by microneedling assisted topical bleomycin. group (B) were treated by cryotherapy. Follow-up was made at the third and the sixth month to