الفهرس 
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Abstract
Viral warts are one of the most common skin diseases. They are caused by the human papilloma virus. While warts are not harmful and usually go away in time without any treatment, they are unattractive and can be painful. Dendritic (DC), Langerhans (LC), natural killer (NK), natural killer T (NKT) cells and keratinocytes, are important cells involved in promoting a good adaptive immune response against HPV infection. These cells capture antigen and transport them to draining lymph nodes where they are presented to T cells.
IL-36γ has been shown to be implicated in the pathogenesis of various inflammatory skin diseases but was poorly investigated in cutaneous warts.
So, the aim of this study was to highlight the possible role of IL- 36γ in the antiviral immune response against HPV infections and to improve the management of this infection.
This analytic case control study was carried out in Dermatology outpatient clinics, Suez Canal University Hospitals, Ismailia city, Egypt. The study included forty patients that attended the Dermatology Outpatient Clinic, Suez Canal University hospitals presenting with warts that were diagnosed by a trained dermatologist and 40 healthy controls. Patients or their legal guardians filled a written consent to participate in the study after receiving full information on the setup and the purpose of the study. Serum level of IL-36γ was measured by ELISA.
61higher serum levels of IL-