الفهرس 
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Abstract
The present study was a one year cross sectional study aimed to evaluate siMS score as a screening method of metabolic syndrome in children and adolescent with simple obesity who attended to the outpatient Nutrition clinic or admitted to the Nutrition unit at Assiut University Children Hospital (NICU) in the period from 1st of January 2020 up to the end of December 2020. The study included 50 children and adolescent with simple obesity (BMI is >95th percentile).
The mean age of the studied participants was 10.05 ± 2.01 years (range: 7 to 16 years old), more than half of the studied cases were ≥ 10 years old, with slight female predominance (male:female ratio of 1:1.5). Twenty percent of the studied cases had positive family history of obesity.
The primary aim of the present study was to evaluate the role of siMS score as a screening method of metabolic syndrome in children and adolescent with simple obesity. The mean siMS score was significantly higher among patients who developed MetS compared to patients with no MetS. Also among patients with MetS; siMS score shows significant negative correlation with HDL level, and significant positive correlation with triglyceride level.
Among 50 studied cases with simple obesity; 24 cases (48%) were diagnosed to developed metabolic syndrome and 26 cases (52%) didn’t developed metabolic syndrome, with no significant difference between both groups regarding age, sex, and family history of obesity. While patients who developed MetS have higher fasting blood glucose, and Triglyceride levels compared to patients without MetS.
Also the predictive ability of siMS for prediction of MetS by using the ROC curve analysis revealed that; at a cutoff value of 3.0 the areas under the ROC curves was 87.0% with a sensitivity of 87.5%, and a specificity of 73.1%, which meaning that siMS was a good predictor for development of MetS among pediatric patients with simple obesity.