الفهرس 
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Abstract
Systemic hypertension induces a progressive increase of left
ventricular (LV) mass with subsequent LV hypertrophy (LVH) with
resulting derangement of LV function. The interaction between left
ventricle (LV) and arterial system, termed usually ventricular-arterial
coupling, and is recognized nowadays as a key determinant of global
cardiovascular performance.
The ventricular-arterial coupling is commonly calculated by the ratio
of effective arterial elastance (EA), a measure of afterload, to LV endsystolic elastance (EES), a relatively load independent measure of LV
chamber performance. LV and arterial system are optimally coupled to
produce stroke work,
The ventricular-arterial coupling has independent prognostic value in
patients with arterial hypertension. Assessment of VAC via EA/EES,
noninvasively can be used for risk stratification of patients with
hypertension. LV deformation as strain can be used for early detection and
quantification of myocardial dysfunction of different etiologies
We aimed in this study to assess the effect of hypertension on left
ventricular mechanical & Ventricular-arterial coupling by using Speckle
tracking imaging technique.
The study conducted on 75 hypertensive patients and 25 control
subjects, Echocardiography performed using a Vivid E9 ultrasound and
Conventional ECHO was done (2D- M mode – Doppler study) for all
participants.
The present study assessed left ventricular peak systolic strain in
hypertensive patients and controls and found that there was significant lower between hypertensive patients and controls as regards all parameters
of left ventricular peak systolic strain.
Hypertension increase left ventricle & arterial stiffness led to
changes in left ventricular mechanism which are correlated decrease the
Global longitudinal strain.