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العنوان
Fibrinogen to Albumin Ratio as a Predictor of No Reflow in STEMI Patients undergoing Primary Percutaneous Coronary Intervention /
المؤلف
Rasheed, Ali El-Ghareeb Mohamed .
هيئة الاعداد
باحث / على الغريب محمد رشيد
مشرف / أ.د / محمود على سليمان
مشرف / أ.د / أحمد عبد العزيز عمارة
مشرف / أ.م. د / هند الديب
الموضوع
Percutaneous Coronary Intervention. Acute Coronary Syndrome therapy. Heart Diseases Treatment.
تاريخ النشر
2024.
عدد الصفحات
76 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
أمراض القلب والطب القلب والأوعية الدموية
تاريخ الإجازة
11/2/2024
مكان الإجازة
جامعة المنوفية - كلية الطب - أمراض القلب والأوعية الدموية
الفهرس
Only 14 pages are availabe for public view

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from 104

Abstract

Summary  This is a Prospective study that used the data of 100 patients between January 2023 and July 2023 who were admitted to Menoufia Cardiovascular center and Al-Araby cardiac unit with a diagnosis of acute STEMI and were candidates for primary Percutaneous Coronary Intervention.  The study included Patients diagnosed as acute STEMI, presented within 12h. of symptom onset who are candidates for Primary PCI with no contraindications and did not receive thrombolytic therapy.  Fibrinogen to Albumin ratio was calculated for every patient.  candidate patients for PPCI underwent coronary angiography, performed in different orthogonal projections using Judkin’s technique then Primary PCI was done using drug eluting stents.  Correlations were made between the calculated Fibrinogen to Albumin Ratio and the No reflow Phenomenon with TIMI II flow or less after PCI.  We found that there is a strong independent positive correlation of FAR to No Reflow Phenomenon being an Excellent Marker in predicting No reflow phenomenon in STEMI patients who underwent PPCI with cutoff value of 10.55 above which it can predict No reflow with sensitivity 100% and specificity 75% and area under the curve 99 %.  We concluded that FAR is a simple, basic and promptly accessible method to anticipate the Possibility of No reflow Phenomenon in STEMI patient undergoing PPCI with a fundamental positive correlation with No reflow and therefore should be used in clinical practice.
Summary
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 The study has some limitations. First, the sample size is very small, and so the results shown in this study should be verified in larger clinical trials. Second, there are multiple risk factors for the No reflow that we did not assess them and it might have affected our multivariate analysis.