الفهرس 
Aim of the workOnly 14 pages are availabe for public view
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Abstract
This study delves comprehensively into the demographic, clinical,
and laboratory aspects of post-kidney transplanted recipients, offering a
nuanced exploration of their characteristics and postoperative outcomes.
The diverse sample of 41 recipients, with a mean age of 29.63 years,
reflects the complexity of this patient population, encompassing various
chronic kidney disease etiologies and comorbidities, most notably
hypertension. The study’s findings provide a valuable snapshot of the
preoperative landscape, emphasizing the predominance of non-smokers and
revealing intriguing autoimmune markers, with negative complement C3
and C4 levels and low prevalence of positive autoantibodies.
Operative details underscore the efficiency of the transplantation
process, with a short mean total ischemia time, a high percentage of cases
not requiring intra-operative blood transfusion, and an encouraging
incidence of immediate diuresis. The predominant use of tacrolimus as an
immunosuppressive agent aligns with established protocols, yet the
variations in induction types add complexity to the immunomodulatory
approaches employed.
The postoperative phase is meticulously explored, revealing a
dynamic pattern of electrolyte and acid-base disturbances. Within the first
month, a substantial proportion of cases experienced hyponatremia,
hypomagnesemia, and hypophosphatemia, alongside a notable prevalence
of metabolic acidosis. Beyond six months, hyperkalemia and
hypercalcemia become more prevalent, emphasizing the evolving nature of
post-transplant metabolic challenges. Significantly higher levels of various
markers at six months compared to the first month suggest an overall
improvement in metabolic and electrolyte homeostasis over time, providing
valuable insights for postoperative management.
The association between blood tacrolimus levels and bicarbonate
abnormalities adds a layer of complexity to our understanding of
immunosuppressive therapy and its impact on metabolic parameters.
However, the study’s limitations, including a small sample size and singlecenter design, underscore the need for caution in generalizing the findings.
The recommendations for future research, advocating for multi-center
studies, extended follow-up periods, and a focus on comparative analyses
of immunosuppressive regimens, offer a roadmap for advancing our
understanding of postoperative complications in kidney transplant
recipients. In conclusion, this study contributes valuable data to the
evolving landscape of kidney transplantation, providing a foundation for future investigations aimed at optimizing care strategies and improving
outcomes for this vulnerable patient population.