الفهرس 
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Abstract
Glaucoma affects more than 70 million people worldwide with
approximately 10% being bilaterally blind, making it the cause of
irreversible blindness in the world. With the growing burden of glaucoma,
we looked for better tools for early diagnosis and monitoring.
Optical coherence tomography angiography (OCTA) is one of the
latest non-invasive imaging technique for studying the vasculature of the
retina, the optic nerve, and the peripapillary region.
It has been shown that glaucoma is related to the reduction in
ocular blood flow but before the advent of OCTA, this has been a difficult
area to study. Most of the previous studies of OCTA in glaucoma looked
at the vessel density (VD) of the optic nerve head and the peripapillary
region.
The aim of this study is to evaluate early macular circulation
changes in open-angle glaucoma (OAG), normal-tension glaucoma
(NTG), ocular hypertension (OHT), and healthy subjects via optical
coherence tomography angiography (OCTA).
One hundred-fifty two eyes of ninty-one female and sixty-one male
participants were enrolled in this study.
Participants were divided into four groups, participants of open
angle glaucomatous eyes, normal- tension glucomatous eyes, ocular
hyper tension eyes and normal eyes, each of them included 38 eyes.
There were statistically significant difference in BCVA between
open angle glaucoma, normal tension glaucoma subjects (p<0.001), and
those with ocular hyper tension and normal subjects.
Statistically significant decrease in both mean RNFL thickness and
GCC were detected in open angle glaucoma and normal tension glaucoma
subjects (p<0.001), compared to ocular hypertension and normal subjects.
The results of our study showed a statistically significant decrease
in VD in both, superficial and deep macular regions in open angle
glaucoma and normal tension glaucoma subjects (p<0.001), while showed
no evidence of decreased macular perfusion in ocular hyper tension
subjects.
Also our results showed no statistically difference in FAZ diameter
between glaucoma, normal and ocular hyper tension subjects (p=0.173).
All of this signify the potential role of OCTA in both diagnosing
and monitoring glaucoma, and get OCTA a foothold in more future
studies evaluating its usefulness.