الفهرس 
IntroductionOnly 14 pages are availabe for public view
 |  | from | 185 |  |  |
| | | from | 185 | | |
Abstract
Mycosis fungoides (MF) is the most common of the primary cutaneous T-cell lymphomas, that constitutes 50% of all primary NHL of the skin. It usually occurs in old adults with a 2:1 male to female ratio. Cells of origin are mature, post-thymic , skin homing, effector memory T cells. Its prognosis is variable and strongly conditioned by the extent and type of skin involvement and presence of extracutaneous disease.
MF presents as cutaneous eruption with erythematosus scaly patches or plaques. The initial lesions are often confined to sun-protected areas.
Histopathologic diagnosis of early MF is one of the most debated issues in dermatopathology. We must exclude inflammatory dermatitis (in particular spongiotic, psoriasiform, chronic dermatitis and lichenoid diseases) and drug induced reactions. The identification of a marker that can reliably distinguish early MF from its inflammatory mimickers has been elusive.
Our study included 75 cases, divided into 2 groups. The first group included 35 patients diagnosed as mycosis fungoides, their mean ages were 44.8±17.1 (range from 3 to 67 years and 62.9% of them were males.
The second group included 40 patients diagnosed as benign inflammatory dermatoses in the form of: Psoriasis, Lichen planus and chronic dermatitis, their mean age was 44.1±11.9 (range from 21 to 70 years).