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Abstract Morbid obesity is defined as obesity with a body mass index ≥40, or ≥35 with secondary diseases. Conservative medical therapies in these individuals generally fail to sustain weight loss. Thus, surgical operations have evolved, which are based on gastric restriction and/or malabsorption . Bariatric surgery is currently the most effective treatment to achieve substantial and long-term weight loss in patients with severe obesity, and it also has beneficial effects on obesity-associated comorbidities such as type 2 diabetes, cardiovascular disease, and cancer. LSG is emerging to be one of the most commonly performed bariatric procedures worldwide. This restrictive procedure has several advantages. It is technically simpler to perform without the need for an anastomosis. It has been reported to have a lower morbidity and mortality rate in comparison to Roux-en-Y gastric bypass or biliopancreatic diversion with or without duodenal switch. It can be performed concomitantly with other procedures. IGB has widely been used as a minimally invasive procedure for the treatment of overweight or obese individuals. It is considered a preferred method by many due to its safety, tolerability, and relatively low cost, bridging the gap between conventional methods and bariatric surgery. Balloon insertion should be considered carefully in patients with large hiatus hernia, inflammatory bowel disease, and increased risk of upper GI bleed, drug/alcohol abuse, and uncontrolled psychiatric disease. Several studies have demonstrated the efficacy and safety of IGBs for temporary weight reduction with low mortality and morbidity. The present study aimed to compare early outcomes of the laparoscopic sleeve gastrectomy with the endoscopic intra-gastric balloon in patients with morbid obesity regarding the degree of weight loss in the first year, patient’s satisfaction, and complications. This prospective study involved 60 consecutive patients who underwent either LSG or IGB insertion. The patients were divided into two groups: the LSG group, comprising thirty patients who underwent laparoscopic sleeve gastrectomy, and the IGB group, including thirty patients who underwent intra-gastric balloon insertion. A short-term followup was conducted for all patients over one year. |