الفهرس 
AbstractOnly 14 pages are availabe for public view
 |  | from | 202 |  |  |
| | | from | 202 | | |
Abstract
The thesis is divided into five main parts:- Part I. Includes general introduction about nanoscience technology and different nanomaterials, such as carbon dots and silver nanoparticles, that could be used as nanosensors and integrated in various applications.
Part II. In this part, we reported a simple, rapid and eco-friendly method for the synthesis of nitrogen and sulfur doped carbon dots (N,S-CDs). The N,S-CDs were utilized as fluorescent probe for determination of the anticoagulant drug, betrixaban maleate (BTM) in bulk, lab-prepared capsules and spiked human plasma based on the quenching of their fluorescence upon its gradual addition. Part III. In this study garlic and red lentils were utilized as natural and inexpensive sources for efficient synthesis of the carbon-based quantum dots using green microwave irradiation. These fluorescent dots were used as a nano-sensor for the determination of the commonly used antibacterial and antiprotozoal drug, metronidazole (MTR). Part IV. The proposed study introduced a simple, fast and eco-friendly method for synthesis of fluorescent silver nanoparticles (Ag-NPs) using Panax Ginseng root extract as a reducing and capping agent. The prepared Ag-NPs were used to assay nilvadipine (NLV) spectrofluorimetrically in its pharmaceutical dosage form with good sensitivity and reproducibility. Part V. In this study, a straight-forward, affordable, sensitive and ecologically friendly spectrofluorimetric method was introduced for determination of BTM at the nano-scale level. The approach is based on turning on the fluorescence of BTM using silver nanoparticles (AgNPs). This approach demonstrated a white analytical insight for quantitative determination of BTM in raw material and lab-prepared capsules.