الفهرس 
AcknowledgementOnly 14 pages are availabe for public view
 |  | from | 173 |  |  |
| | | from | 173 | | |
Abstract
Introduction & Aim of the work It was found that toe web maceration is a common health problem in dermatologic practice in Egypt. (Abdallah et al., 1971; El-Mofty et al., 1975; Mohamed, 1977). Since tinea pedis is not a reportable disease and primary disease is often not diagnosed by physician, exact morbidity figures are difficult to obtain. It was estimated that, worldwide, billions of dollars are spent annually to treat tinea pedis and related complaints (Page et al., 1991). Interdigital toe web infections have been traditionally categorized as caused by inva¬sion of the skin by dermatophytic fungi. This is a gross over-simplification that has adversely I affected diagnosis and treatment (Leyden and Kligman, 1978). Clinically, interdigital toe web I infections, range from relatively asymptomatic mild scaling to exudative, macerated, malodor-i ous conditions. Surprisingly the recovery of fungi from macerated toe web spaces has been low and rarely exceeds 30% in many large series (Marples and Chapman, 1959, Davis et al., 1972, Gentles and Evans, 1973; Leyden and Kligman; 1978; Kates et al., 1990). A flourishing bacterial superinfection may mask the underlying fungal cause, making it difficult to obtain a positive fungal culture and cause maceration , itching and often malodor at the site (kates et al., 1990; Leyden, 1993). Econazole nitrate is a member of the imidazole class of antifimgal drugs. Although econazole is primarily considered an antifimgal agent, there are reports of in vitro antibacterial activity (Heel et al., 1978). It has been mentioned in the Holy Quran that ”There comth from within their bellies a drink of varying hues (meaning the bee honey) wherein is healing for man-kind”. Although today medicinal use of honey is largely confined to folk medicine, there are occasional reports in the modern medical literature describing its value in treatment of wounds, burns, infections.